The country has just taken part in a giant democratic exercise, perhaps the biggest in our history.
Over 33 million people from England, Scotland, Wales, Northern Ireland and Gibraltar, have all had their say.
We should be proud of the fact that in these islands, we trust the people with these big decisions.
We not only have a parliamentary democracy but on questions about the arrangements for how we are governed, there are times when it is right to ask the people themselves, and that is what we have done.
The British people have voted to leave the European Union and there will must be respected.
I want to thank everyone who took part in the campaign on my side of the argument, including all those who put aside party differences to speak in what they believed was the national interest.
And let me congratulate all those who took part in the Leave campaign for the spirited and passionate case that they made.
The will of the British people is an instruction that must be delivered.
It was not a decision that was taken lightly, not least because so many things were said by so many different organisations about the significance of this decision so there can be no doubt about the result.
Across the world, people have been watching the choice that Britain has made.
I would reassure those markets and investors that Britain’s economy is fundamentally strong and I would also reassure Brits living in European countries and European citizens living here that they will be no immediate changes in your circumstances.
There will be no initial change in the way our people can travel, in the way our goods can move or the way our services can be sold.
We must now prepare for a negotiation with the European Union.
This will need to involve a full engagement of the Scottish, Welsh and Northern Ireland governments to ensure that the interests of all parts of our UK are protected and advanced.
But above all, this will require strong, determined and committed leadership.
I am very proud and honoured to have been Prime Minister of this country for six years.